Others
- Thomas W. Murphy (American Samoa judge) (1935–1992), Associate Chief Justice of the High Court of American Samoa
- Thomas W. Murphy (Illinois judge) (born 1953), judge in the Cook County Circuit Court, Chicago
- Thomas Francis Murphy (1905–1995), federal prosecutor and judge in New York City
- Thomas Murphy (chairman) (1915–2006), former CEO of General Motors
- Thomas Joseph Murphy (1932–1997), American bishop in the Catholic Church
- Thomas Austin Murphy (1911–1981), American clergyman of the Roman Catholic Church
- Thomas W. Murphy (anthropologist) (born 1967), Environmental Anthropologist and Latter Day Saint writer
- Tom Murphy (physicist), astrophysicist
- Thomas M. Murphy (1926–2002), U.S. postmaster whose alertness may have saved the life of US President-elect, John F. Kennedy
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