Testicular atrophy is a medical condition in which the male reproductive organs (the testes, which in humans are located in the scrotum) diminish in size and may be accompanied by loss of function. This does not refer to temporary changes, such as those brought on by cold.
Some medications can cause testicular atrophy. Anabolic-Androgenic Steroids (AAS) can cause testicular atrophy by reducing the amount of luteinizing hormone (LH) produced by the pituitary gland. LH stimulates the testicles to produce testosterone. Testicular atrophy caused by steroid use can be prevented by taking hCG, a drug which mimics the effect of LH. However, hCG will simply address the symptoms. Endogenous levels of anabolic-androgenic steroids will remain the cause, and testicular atrophy will continue until the male body regains homeostasis. It is unclear how long hCG can be administered to a male on anabolic-androgenic steroids before desensitization occurs.
Famous quotes containing the words testicular and/or atrophy:
“... the Ovarian Theory of Literature, or, rather, its complement, the Testicular Theory. A recent camp follower ... of this explicit theory is ... Norman Mailer, who has attributed his own gift, and the literary gift in general, solely and directly to the possession of a specific pair of organs. One writes with these organs, Mailer has said ... and I have always wondered with what shade of ink he manages to do it.”
—Cynthia Ozick (b. 1928)
“The three great problems of this century, the degradation of man in the proletariat, the subjection of women through hunger, the atrophy of the child by darkness.”
—Victor Hugo (1802–1885)