Tbx2

TBX2

Identifiers Symbols TBX2; FLJ10169 External IDs OMIM: 600747 MGI: 98494 HomoloGene: 38123 GeneCards: TBX2 Gene

Gene Ontology
Molecular function	• DNA binding • sequence-specific DNA binding transcription factor activity • protein binding • sequence-specific DNA binding
Cellular component	• nucleus • transcription factor complex
Biological process	• negative regulation of transcription from RNA polymerase II promoter • outflow tract septum morphogenesis • outflow tract morphogenesis • endocardial cushion morphogenesis • regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation • transcription, DNA-dependent • muscle cell fate determination • cell aging • positive regulation of cell proliferation • aorta morphogenesis • atrioventricular canal development • embryonic digit morphogenesis • negative regulation of transcription, DNA-dependent • embryonic camera-type eye morphogenesis • cardiac muscle tissue development • palate development • positive regulation of cardiac muscle cell proliferation • pharynx development • developmental growth involved in morphogenesis • mammary placode formation • cellular senescence • negative regulation of heart looping • negative regulation of cardiac chamber formation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6909 21385 Ensembl ENSG00000121068 ENSMUSG00000000093 UniProt Q13207 Q60707 RefSeq (mRNA) NM_005994 NM_009324 RefSeq (protein) NP_005985 NP_033350 Location (UCSC) Chr 17:
59.48 – 59.49 Mb Chr 11:
85.83 – 85.84 Mb PubMed search

T-box transcription factor TBX2 is a protein that in humans is encoded by the TBX2 gene.