A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole. Although most medical conditions will eventually involve multiple organs in advanced stage (e.g. Multiple organ dysfunction syndrome), diseases where multiple organ involvement is at presentation or in early stage are considered elsewhere.
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“The fantasies inspired by TB in the last century, by cancer now, are responses to a disease thought to be intractable and capricious—that is, a disease not understood—in an era in which medicine’s central premise is that all diseases can be cured.”
—Susan Sontag (b. 1933)
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