Suzuki Reaction - Scope

Scope

The Suzuki coupling has been frequently used in syntheses of complex compounds. The Suzuki coupling has been used on a citronellal derivative for the synthesis of caparratriene, a natural product that is highly active against leukemia:

Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis have been summarized by Kotha and co-workers. With a novel organophosphine ligand (SPhos), a catalyst loading of down to 0.001 mol% has been reported:

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