Structure
Its C-terminus contains a StAR-related transfer domain (START) that is homologous to the StAR. X-ray crystallography of the C-terminus indicates that this domain forms a pocket that can bind cholesterol. This places MLN64 within the StarD1/D3 subfamily of START domain-containing proteins.
The N-terminus consists of a MENTAL (MLN64 N-terminal) domain similar to the protein MLN64 N-terminal homologue (MENTHO) with unclear function. This domain is buried in the late endosomal membrane and may associate with the same domain in MENTHO.
Read more about this topic: STARD3
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