SRI (gene)

SRI (gene)

Identifiers Symbols SRI; CP-22; CP22; SCN; V19 External IDs OMIM: 182520 MGI: 98419 HomoloGene: 37736 GeneCards: SRI Gene

Gene Ontology
Molecular function	• protease binding • receptor binding • calcium channel regulator activity • calcium ion binding • protein binding • ion channel binding • protein heterodimerization activity
Cellular component	• cytoplasm • endoplasmic reticulum membrane • cytosol • membrane • sarcoplasmic reticulum • Z disc • T-tubule • sarcoplasmic reticulum membrane • chromaffin granule membrane
Biological process	• regulation of action potential • transport • calcium ion transport • intracellular sequestering of iron ion • regulation of striated muscle contraction • signal transduction • heart development • muscle organ development • regulation of heart contraction • negative regulation of heart rate • regulation of cell communication by electrical coupling • regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum • regulation of calcium ion transport • negative regulation of ryanodine-sensitive calcium-release channel activity • regulation of cardiac muscle cell contraction • regulation of relaxation of muscle • regulation of voltage-gated calcium channel activity • regulation of cell communication by electrical coupling involved in cardiac conduction
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6717 109552 Ensembl ENSG00000075142 ENSMUSG00000003161 UniProt P30626 Q6P069 RefSeq (mRNA) NM_001256891 NM_001080974 RefSeq (protein) NP_001243820 NP_001074443 Location (UCSC) Chr 7:
87.83 – 87.86 Mb Chr 5:
8.05 – 8.07 Mb PubMed search

Sorcin is a protein that in humans is encoded by the SRI gene.