Somatostatinoma

Somatostatinoma is a tumor of the delta cells of the endocrine pancreas that produces somatostatin.

It is associated with diabetes mellitus and abnormal glucose tolerance.

Triad of : Mild diabetes mellitus, steatorrhoea, gall stones. also associated with hypochlorhydria.

Commonly found in head of pancreas, and are malignant.

Elevated plasma levels of Somatostatin.

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