Clinical Significance
In one study, deletions in the gene were reported in two familial cases of keratoconus.
Mice lacking SOD1 have increased age-related muscle mass loss (sarcopenia), early development of cataracts, macular degeneration, thymic involution, hepatocellular carcinoma, and shortened lifespan.
Read more about this topic: SOD1
Famous quotes containing the word significance:
“History is the interpretation of the significance that the past has for us.”
—Johan Huizinga (1872–1945)