Small Nucleolar RNA SNORD23 (also known as HBII-115) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifiying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
SNORD23 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the C/D box family function in directing site-specific 2'-O-methylation of substrate RNAs. This snoRNA is the human orthologue of mouse snoRNA MBII-115. There is currently no predicted target RNA for SNORD23.
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“You—poor and obscure, and small and plain as you are—I entreat to accept me as a husband.”
—Charlotte Brontë (1816–1855)