SF3B4
Gene Ontology | |
---|---|
Molecular function | • nucleotide binding • RNA binding • protein binding |
Cellular component | • nucleoplasm • spliceosomal complex • U12-type spliceosomal complex |
Biological process | • RNA splicing, via transesterification reactions • mRNA splicing, via spliceosome • mRNA processing • RNA splicing • gene expression |
Sources: Amigo / QuickGO |
149.9 – 149.9 Mb
96.17 – 96.18 Mb
Splicing factor 3B subunit 4 is a protein that in humans is encoded by the SF3B4 gene.
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Read more about SF3B4: Disease Associations, Interactions