Serum Amyloid P Component

Serum Amyloid P Component

Identifiers Symbols APCS; PTX2; SAP External IDs OMIM: 104770 MGI: 98229 HomoloGene: 123932 ChEMBL: 4929 GeneCards: APCS Gene

Gene Ontology
Molecular function	• metal ion binding • unfolded protein binding
Cellular component	• extracellular region • extracellular space • extracellular matrix • protein complex
Biological process	• protein folding • acute-phase response • chaperone-mediated protein complex assembly
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 325 20219 Ensembl ENSG00000132703 ENSMUSG00000026542 UniProt P02743 P12246 RefSeq (mRNA) NM_001639 NM_011318 RefSeq (protein) NP_001630 NP_035448 Location (UCSC) Chr 1:
159.56 – 159.56 Mb Chr 1:
172.89 – 172.9 Mb PubMed search

Amyloid P component, serum (SAP) is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". APCS is its human gene.