SEC24D

Identifiers Symbols SEC24D; FLJ43974; KIAA0755 External IDs OMIM: 607186 MGI: 1916858 HomoloGene: 40986 GeneCards: SEC24D Gene

Gene Ontology
Molecular function	• molecular_function • zinc ion binding
Cellular component	• Golgi membrane • endoplasmic reticulum membrane • cytosol • ER to Golgi transport vesicle membrane • COPII vesicle coat • perinuclear region of cytoplasm
Biological process	• antigen processing and presentation of peptide antigen via MHC class I • intracellular protein transport • ER to Golgi vesicle-mediated transport • cellular membrane organization • protein N-linked glycosylation via asparagine • antigen processing and presentation of exogenous peptide antigen via MHC class II • post-translational protein modification • cellular protein metabolic process • small molecule metabolic process • COPII vesicle coating
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 9871 69608 Ensembl ENSG00000150961 ENSMUSG00000039234 UniProt O94855 Q6NXL1 RefSeq (mRNA) NM_014822 NM_027135 RefSeq (protein) NP_055637 NP_081411 Location (UCSC) Chr 4:
119.64 – 119.76 Mb Chr 3:
123.27 – 123.37 Mb PubMed search

Protein transport protein Sec24D is a protein that in humans is encoded by the SEC24D gene.

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The role of this gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration.