S
- Saint Jude's Infirmary, indie band
- Emeli Sandé, singer
- Mary Sandeman (aka Aneka), Traditional singer, solo and with Scottish Fiddle Orchestra, Gaelic Mod Gold Medallist
- Michael Sandison (born 1970), electronic musician, Boards of Canada
- Saor Patrol, folk band
- Paul Savage drummer in The Delgados
- Scars, band
- Bon Scott (1946–1980) singer for band AC/DC
- Mike Scott (born 1958)
- ScottishPower Pipe Band
- The Secret Goldfish
- Sensational Alex Harvey Band
- Rachel Sermanni
- The Shamen
- Jimmy Shand (1908–2000)
- Donald Shaw
- Eilidh Shaw, fiddle player and singer
- The Shermans
- Derek Shulman, lead singer for Simon Dupree and the Big Sound and Gentle Giant
- The Silencers
- Simple Minds
- Tom Simpson, Keyboardist for Snow Patrol
- The Singing Kettle, folk music group
- Skids, band
- Slam House and Techno DJs/Producers
- Slik - Midge Ure's first band
- Sluts of Trust
- Emily Smith, singer
- Martin Smith (1957-1994)
- Tommy Smith jazz saxophonist, composer, educator and bandleader (Scottish National Jazz Orchestra)
- David Sneddon, singer/songwriter
- Snow Patrol
- Snowblood, sludge/post-rock/doom metal band
- Jimmy Somerville
- Sons and Daughters, band
- Soup Dragons band
- Spare Snare, band
- Spartan Tartan
- Spirea X - Greenock psychedelic band
- Sharleen Spiteri, singer/musician from the band Texas
- Isla St Clair
- Adam Stafford, lead singer of Y'all is Fantasy Island
- Stanley Odd, alternative hip-hop group
- Mike Starrs
- Eilidh Steel fiddler
- Al Stewart
- Andy Stewart (1933–93)
- Andy M. Stewart singer, formerly of Silly Wizard
- Ian Stewart, keyboardist and co-founder of The Rolling Stones
- Rachel Stewart, singer and folk dancer, a founding member of Beauty School
- Stiltskin
- Stonedog
- Stone The Crows
- The Stormy Seas
- Chris Stout
- Hamish Stuart
- Strawberry Switchblade band
- Sucioperro, rock band
- The Supernaturals
- Stuart Sutcliffe (1940–1962) original bass player of The Beatles
- Katie Sutherland, singer
- Swanee, elder brother of Jimmy Barnes
Read more about this topic: Scottish Musicians