Characters
- Fuminori Sakisaka (匂坂 郁紀, Sakisaka Fuminori?)
- Voiced by: Hikaru Midorikawa (credited as Hikaru)
- The protagonist of the game. A medical school student, he suffers a near-fatal traffic accident which kills his parents and leaves his perception of life permanently altered. As he wades through a "world gone berserk" of flesh and blood, he seeks the affection of the only thing he sees as normal — a mysterious girl named Saya, whom he falls madly in love with. Over time due to Saya's influence, Fuminori views normal people with apathetic disdain and becomes willing to kill others without remorse with only Saya and later, Yō as exceptions. Over the course of the events, he gradually becomes a ruthless cannibal, finding human flesh delicious through his twisted senses.
- Saya (沙耶, Saya?)
- Voiced by: Naoko Takano (credited as Midori Kawamura)
- Saya is a being from another dimension who materialized in this universe for the sole purpose of reproduction. She has no memories of where she came from and is guided only by her instincts. Due to Fuminori's condition, he perceives her as a lithe young girl in a white dress, but in actuality she is some sort of amorphous, tentacled, fleshy abomination that emits a putrid stench. She preys on creatures of all sizes, from cats to human beings, typically killing them by snapping their necks or disembowelment through some unknown means, and then feasting on their internal organs. She is apparently capable of projecting a strong acid which she uses to partially digest her food before consuming it, and, in one case, to infiltrate a house by melting the glass of a window. Her true form is never fully revealed, as she immediately kills and consumes any third-party observers and notably because her visage is incomprehensible to humans, rendering them insane. The small amount of information regarding her actual form is gleaned entirely from in-game descriptions, which themselves are rather vague and never go into detail.
- Kōji Tonoo (戸尾 耕司, Tonoo Kōji?)
- Voiced by: Yasunori Matsumoto
- Fuminori's friend. After Fuminori's accident he has been trying to help Fuminori's life get back to normal. However, after Kōji is almost killed by Fuminori and learns the truth of Fuminori's new character, Kōji directly confronts Fuminori's actions and attempts to kill him.
- Ōmi Takahata (高畠 青海, Takahata Ōmi?)
- Voiced by: Hyo-sei (Credited as Erena Kanbara)
- Kōji's girlfriend and Yō's best friend. After Fuminori's accident she has become worried for Yō's sake. After Fuminori blatantly rejects Yō, Ōmi investigates by going to Fuminori's house. Inside Fuminori's house, Ōmi is killed by Saya. And eaten by Saya and Fuminori.
- Yō Tsukuba (津久葉 瑶, Tsukuba Yō?)
- Voiced by: Mio Yasuda
- A friend of Fuminori's who has a crush on him. Since his accident she has been worried and heartbroken at his sudden change of attitude towards the world. When she goes to investigate the disappearance of Ōmi, Yō is captured by Saya. Yō is subjected to an experiment by Saya and becomes genetically altered into the same type of creature as Saya after over 20 hours of hideous transformation. Fuminori was then able to view Yō as he originally did afterwards. However, the change caused Yō unbearable pain and she begged Kōji to kill her later in the story. However, Kōji's mind snaps from the sight of her monstrous form and he beats her to death with a rusty iron pipe in his horror and confusion. As the first ending takes place before Yoh is captured and mutated by Saya, Yoh isn't mutated or killed in that ending.
- Ryōko Tanbo (丹保 凉子, Tanbo Ryōko?)
- Voiced by: Mitsuki Saiga
- The physician in charge of Fuminori's condition. She becomes suspicious that Fuminori has been hiding something during his routine checkups after he recovers from his injuries.
Read more about this topic: Saya No Uta
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