Entertainment
- Sam, one half of the Freelance Police duo known as Sam & Max
- Sam (1976 film), a 1976 film directed by Larry Buchanan
- Sam (film), a 1986 documentary film
- Sam Puckett, a fictional character in the TV show iCarly
- Sam Gamgee, a.k.a. Samwise Gamgee and Samwise Gardner, a fictional character in J. R. R. Tolkien's legendarium
- "Sam" (Meat Puppets song), 1991
- "Sam" (Olivia Newton-John song), 1977
- Sam (Osvajači album), 1995
- Sam (Škabo album), 2003
- Sam (Trick 'r Treat), the main character in the horror movie Trick 'r Treat
- Sam (1973 TV series), a 1973 British television drama series
- Sam (1978 TV series), an American crime drama television series
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