RNA-induced Silencing Complex

RNA-induced silencing complex, or RISC, is a multiprotein complex that incorporates one strand of a small interfering RNA (siRNA) or microRNA (miRNA). RISC uses the siRNA or miRNA as a template for recognizing complementary mRNA. When it finds a complementary strand, it activates RNase and cleaves the RNA. This process is important both in gene regulation by microRNAs and in defense against viral infections, which often use double-stranded RNA as an infectious vector.

Read more about RNA-induced Silencing Complex:  Strands, Binding

Famous quotes containing the words silencing and/or complex:

    The peculiar evil of silencing the expression of an opinion is, that it is robbing the human race; posterity as well as the existing generation; those who dissent from the opinion, still more than those who hold it. If the opinion is right, they are deprived of the opportunity of exchanging error for truth: if wrong, they lose, what is almost as great a benefit, the clearer perception and livelier impression of truth, produced by its collision with error.
    John Stuart Mill (1806–1873)

    I have met charming people, lots who would be charming if they hadn’t got a complex about the British and everyone has pleasant and cheerful manners and I like most of the American voices. On the other hand I don’t believe they have any God and their hats are frightful. On balance I prefer the Arabs.
    Freya Stark (1893–1993)