C
- Cale Young Rice (1872–1943), U.S. poet and dramatist
- Caleb Rice (1792–1873), attorney and politician who was first president of the Massachusetts Mutual Life Insurance Company
- Cecil Spring-Rice (1872–1943) British diplomat.
- Charles Allen Thorndike Rice (1851–1889), publisher, editor and journalist
- Charles Owen Rice (1908–2005), U.S. labor activist, Roman Catholic priest
- Chester W. Rice (1888–1951), U.S. inventor
- Chris Rice, U.S. singer and songwriter of contemporary and Christian music
- Christopher Rice (born 1978), U.S. novelist, son of Anne Rice
- Clive Rice (born 1949), a former South African cricketer
- Condoleezza Rice (born 1954), U.S. academic and public official, former Secretary of State
- Constance L. Rice (born 1956), U.S. civil rights activist
- Craig L. Rice, (born 1972), U.S. politician from Maryland
- Craig Rice (author) (1908–1957), U.S. author of mysteries
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