Synthesis of The Ribophorins
The synthesis of ribophorins is carried out in the cytoplasm and each kind of ribophorin has a different gen. This way, ribophorin I is encoded by the RPN1 gen. Otherwise, ribophorin II is encoded by the RPN2 gen. Moreover, each gen will translate a signal sequence to indicate the ribophorin destiny. In the case of humans, the sequence is formed by 23 amino acids for ribophorin I; and in ribophorin II, it has 22 aminoacids.
In the chromosome, the gens are displayed in a specific locus; so that, in humans RPN1 is located at 3q21.3 (in chromosome 3) and RPN2 is found at the locus 20q12-q13.1 (in chromosome 20). In total, ribophorin I and II are composed by 607 and 632 amino acids respectively.
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