Repression of Heat Shock Gene Expression (ROSE) Element - ROSE1 and ROSEAT2

ROSE1 and ROSEAT2

ROSE1 and ROSEAT2 are specific examples of ROSE elements. ROSE1 is found in Bradyrhizobium japonicum whereas ROSEAT2 is a closely related element from Agrobacterium tumefaciens. The two RNA elements have similar secondary structures with ROSE1 having an extra hairpin. All ROSE elements contain a characteristic 'bulged G' opposite the Shine-Dalgarno sequence binding site, without this nucleotide the RNA thermometer loses its temperature-sensitivity.

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