Subjects For Scientific Research
In 1895, Clark University in Worcester, Massachusetts (United States) established a population of domestic albino brown rats to study the effects of diet and for other physiological studies. Over the years, rats have been used in many experimental studies, which have added to our understanding of genetics, diseases, the effects of drugs, and other topics that have provided a great benefit for the health and well-being of humankind. Laboratory rats have also proved valuable in psychological studies of learning and other mental processes (Barnett, 2002), as well as to understand group behavior and overcrowding (with the work of John B. Calhoun on behavioral sink). A 2007 study found rats to possess metacognition, a mental ability previously only documented in humans and some primates.
Domestic rats differ from wild rats in many ways. They are calmer and less likely to bite; they can tolerate greater crowding; they breed earlier and produce more offspring; and their brains, livers, kidneys, adrenal glands, and hearts are smaller (Barnett 2002).
Brown rats are often used as model organisms for scientific research. Since the publication of the rat genome sequence, and other advances, such as the creation of a rat SNP chip, and the production of knockout rats, the laboratory rat has become a useful genetic tool, although not as popular as mice. When it comes to conducting tests related to intelligence, learning, and drug abuse, rats are a popular choice due to their high intelligence, ingenuity, aggressiveness, and adaptability. Their psychology, in many ways, seems to be similar to humans. Entirely new breeds or "lines" of brown rats, such as the Wistar rat, have been bred for use in laboratories. Much of the genome of Rattus norvegicus has been sequenced.
Read more about this topic: Rat
Famous quotes containing the words subjects for, subjects, scientific and/or research:
“Despite the hundreds of attempts, police terror and the concentration camps have proved to be more or less impossible subjects for the artist; since what happened to them was beyond the imagination, it was therefore also beyond art and all those human values on which art is traditionally based.”
—A. Alvarez (b. 1929)
“When life has been well spent, age is a loss of what it can well spare,—muscular strength, organic instincts, gross bulk, and works that belong to these. But the central wisdom, which was old in infancy, is young in fourscore years, and dropping off obstructions, leaves in happy subjects the mind purified and wise.”
—Ralph Waldo Emerson (1803–1882)
“A superstition which pretends to be scientific creates a much greater confusion of thought than one which contents itself with simple popular practices.”
—Johan Huizinga (1872–1945)
“Our science has become terrible, our research dangerous, our findings deadly. We physicists have to make peace with reality. Reality is not as strong as we are. We will ruin reality.”
—Friedrich Dürrenmatt (1921–1990)