PVRL3
Gene Ontology | |
---|---|
Molecular function | • protein binding • protein homodimerization activity • cell adhesion molecule binding |
Cellular component | • plasma membrane • cell-cell adherens junction • integral to membrane • apical junction complex |
Biological process | • lens morphogenesis in camera-type eye • homophilic cell adhesion • fertilization • cell junction assembly • adherens junction organization • cell-cell junction organization • retina morphogenesis in camera-type eye |
Sources: Amigo / QuickGO |
110.79 – 110.99 Mb
46.39 – 46.5 Mb
Poliovirus receptor-related 3 (nectin-3), also known as PVRL3 and CD113 (Cluster of Differentiation 113), is a human gene.
Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.
Read more about PVRL3: See Also, Interactions