PTS (gene)

PTS (gene)

Identifiers Symbols PTS; PTPS External IDs OMIM: 612719 MGI: 1338783 HomoloGene: 268 GeneCards: PTS Gene EC number 4.2.3.12

Gene Ontology
Molecular function	• 6-pyruvoyltetrahydropterin synthase activity • identical protein binding • protein homodimerization activity • metal ion binding
Cellular component	• cytoplasm • mitochondrion • cytosol
Biological process	• cellular amino acid metabolic process • tetrahydrobiopterin biosynthetic process • central nervous system development • small molecule metabolic process • nitric oxide metabolic process • regulation of nitric-oxide synthase activity
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5805 19286 Ensembl ENSG00000150787 ENSMUSG00000032067 UniProt Q03393 Q9R1Z7 RefSeq (mRNA) NM_000317 NM_011220 RefSeq (protein) NP_000308 NP_035350 Location (UCSC) Chr 11:
112.1 – 112.14 Mb Chr 9:
50.52 – 50.53 Mb PubMed search

6-pyruvoyltetrahydropterin synthase, also known as PTS, is a human gene which facilitates folate biosynthesis.