Psychedelic Research - History

History

Psychedelic substances which may have therapeutic uses include Psilocybin (commonly referred as magic mushrooms), LSD, and MDMA commonly referred to as ecstasy. Although the history behind these substances have hindered research of their potential medicinal value, scientists are now able to conduct studies and renew research that was halted 40 years ago. Some research has shown that these substances have helped people with such mental disorders such as Obsessive Compulsive disorder, Post-Traumatic Stress Disorder, Alcoholism, Depression, and Cluster Headaches. MDMA started out as a tool for therapists to use to let the patient confront the trauma that induced the PTSD. Many successes have come from using these substances in a respectful and professional way, showing that psychedelics contain hidden value that the government was all too quick to dismiss. By researching and continuing to study these substances we may find cures to these mental disabilities.

Psychedelic therapy, in the broadest possible sense of the term, undoubtedly? dates from prehistoric knowledge of hallucinogenic plants. Though usually viewed as predominantly spiritual in nature, elements of psychotherapeutic practice can be recognized in the entheogenic or shamanic rituals of many cultures.

Some of the well known particular psychedelic substances that have been used to this day are: MDMA, LSD, Psilocybin, Cannabis, Mescaline, 2C-B, Dimethyltryptamine, Ibogaine, Gamma-Hydroxybutyric acid, Ketamine, Amanita muscaria, Bufotenine, Harmaline, Ayahuasca, and Salvia divinorum. Carbogen has also played role in psychedelic therapy research. Shamans have historically been well known throughout the world to mix two or more of some of the listed substances to produce synergistic effects. (See Psychoactive, Entheogen, Hallucinogen, Psychotherapy, Psychonaut, Meditation, Trance, Mysticism, Transcendence (philosophy).)

The use of psychedelic agents in Western therapy began in the 1950s, after the widespread distribution of LSD to researchers by its manufacturer, Sandoz Laboratories. Research into experimental, chemotherapeutic and psychotherapeutic uses of psychedelic drugs was conducted in several countries over the next 10–15 years. In addition to the release of dozens of books and creation of six international conferences, more than 1000 peer-reviewed clinical papers detailing the use of psychedelic compounds (administered to approximately 40,000 patients) were published by the mid-1960s. Proponents believed that psychedelic drugs facilitated psychoanalytic processes, and that they were particularly useful for patients with problems that were otherwise difficult to treat, including alcoholics, although the trials did not meet the methodological standards required today.

One challenge of psychedelic therapy was the greatly variable effects produced by the drugs. According to Stanislav Grof, "The major obstacle to their systematic utilization for therapeutic purposes was the fact that they tended to occur in an elemental fashion, without a recognizable pattern, and frequently to the surprise of both the patient and the therapist. Since the variables determining such reactions were not understood, therapeutic transformations of this kind were not readily replicable." Attempts to produce these experiences in a controlled, non-arbitrary, predictable way resulted in several methods of psychedelic therapy, which are reviewed below.

Researchers like Timothy Leary felt psychedelics could alter the fundamental personality structure or subjective value-system of an individual, to beneficial effect. His experiments with prison inmates were an attempt to reduce recidivism through a few short, intense sessions of psilocybin administered weeks apart with biweekly group therapy sessions in between. Psychedelic therapy was used in a number of other specific patient populations, including alcoholics, children with autism, and people with terminal illness.