Entertainment
- Psi (comics), a character in DC Comics
- Psi Com, a 1980s rock band
- Psi Corps, in the Babylon 5 fictional universe, the ruling body of Earth's telepaths
- Psi Division, a division in the Judge Dredd and 2000 AD series of comics
- Psi Factor: Chronicles of the Paranormal, a Canadian television series
- Psi-Force, a comic series
- Psi-Hawk, a comic character
- Psi Lords, a comic series
- Psi-Ops: The Mindgate Conspiracy, a video game in which characters use psychic powers
- Psi Power, a 1978 song by the UK rock group Hawkwind
- PSI, the psychic power used by some characters in the EarthBound series
- PSI (album), an album by Pitchshifter
- PSI Records, a music record label
- PSI, Petra Sedilkova Illusions']]
- PSY (rapper)
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