Procaine Benzylpenicillin - Uses

Uses

Specific indications for procaine penicillin include:

• Syphilis
  • In the United States, Bicillin C-R (a injectable suspension which 1.2 million units of benzathine penicillin and 1.2 million units of procaine penicillin per 4 ml) is not recommended for treating syphilis, since it contains only half the recommended dose of benzathine penicillin. Medication errors have been made due to the confusion between Bicillin L-A & Bicillin C-R. As a result, changes in product packaging have been made; specifically, the statement "Not for the Treatment of Syphilis" has been added in red text to both the Bicillin CR and Billin CR 900/300 syringe labels.
• Respiratory tract infections where compliance with oral treatment is unlikely
• Alongside Pen V and Erythromycin, Bicillin C-R is used to treat strep throat, given as one IM injection
• Cellulitis, erysipelas
• Procaine penicillin is also used as an adjunct in the treatment of anthrax.