PPP2R1A

PPP2R1A

Identifiers Symbols PPP2R1A; PP2A-Aalpha; PP2AAALPHA; PR65A External IDs OMIM: 605983 MGI: 1926334 HomoloGene: 68559 GeneCards: PPP2R1A Gene EC number 3.1.3.16

Gene Ontology
Molecular function	• antigen binding • protein serine/threonine phosphatase activity • protein binding • protein phosphatase type 2A regulator activity • protein heterodimerization activity
Cellular component	• protein phosphatase type 2A complex • chromosome, centromeric region • nucleus • mitochondrion • cytosol • microtubule cytoskeleton • membrane
Biological process	• G2/M transition of mitotic cell cycle • M phase of mitotic cell cycle • mitotic anaphase • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • inactivation of MAPK activity • mitotic cell cycle • regulation of DNA replication • regulation of transcription, DNA-dependent • protein complex assembly • protein dephosphorylation • ceramide metabolic process • induction of apoptosis • chromosome segregation • mitotic nuclear envelope reassembly • RNA splicing • fibroblast growth factor receptor signaling pathway • response to organic substance • gene expression • RNA metabolic process • mRNA metabolic process • second-messenger-mediated signaling • regulation of Wnt receptor signaling pathway • regulation of cell adhesion • negative regulation of cell growth • regulation of growth • negative regulation of tyrosine phosphorylation of Stat3 protein • regulation of cell differentiation • peptidyl-serine dephosphorylation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5518 51792 Ensembl ENSG00000105568 ENSMUSG00000007564 UniProt P30153 Q76MZ3 RefSeq (mRNA) NM_014225 NM_016891 RefSeq (protein) NP_055040 NP_058587 Location (UCSC) Chr 19:
52.69 – 52.73 Mb Chr 17:
20.95 – 20.97 Mb PubMed search

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform is an enzyme that in humans is encoded by the PPP2R1A gene. In the plant Arabidopsis thaliana a similar enzyme is encoded by the RCN1 gene (At1g25490).