Ppp1ca

PPP1CA

Identifiers Symbols PPP1CA; PP-1A; PP1A; PP1alpha; PPP1A External IDs OMIM: 176875 MGI: 103016 HomoloGene: 105262 ChEMBL: 2164 GeneCards: PPP1CA Gene EC number 3.1.3.16

Gene Ontology
Molecular function	• protein serine/threonine phosphatase activity • protein binding • ribonucleoprotein complex binding • metal ion binding
Cellular component	• protein phosphatase type 1 complex • nucleus • nucleolus • cytoplasm • cytosol • glycogen granule • dendritic spine • perikaryon • MLL5-L complex • PTW/PP1 phosphatase complex
Biological process	• glycogen metabolic process • regulation of glycogen biosynthetic process • regulation of glycogen catabolic process • protein dephosphorylation • lipid metabolic process • cell cycle • transforming growth factor beta receptor signaling pathway • triglyceride catabolic process • lung development • negative regulation of transforming growth factor beta receptor signaling pathway • small molecule metabolic process • branching morphogenesis of an epithelial tube • cell division
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5499 19045 Ensembl ENSG00000172531 ENSMUSG00000040385 UniProt P62136 P62137 RefSeq (mRNA) NM_001008709 NM_031868 RefSeq (protein) NP_001008709 NP_114074 Location (UCSC) Chr 11:
67.17 – 67.19 Mb Chr 19:
4.19 – 4.2 Mb PubMed search

Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene.