Early Career
In 1507 he was appointed tutor to Emperor Maximilian I's (1493–1519) seven year old grandson, Charles, who was later to become Emperor Charles V (1519–56). In 1515 Adrian was sent to Spain on a diplomatic errand, and after his arrival at the Imperial Court in Toledo, Charles V secured his succession to the See of Tortosa, and on 14 November 1516 commissioned him Inquisitor General of Aragon. The following year, Pope Leo X (1513–21) made Adrian a cardinal, naming him Cardinal Priest of the Basilica of Saints John and Paul.
During the minority of Charles V, Adrian was named to serve with Cardinal Francisco Jimenez de Cisneros as co-regent of Spain. After the death of Jimenez, Adrian was appointed (14 March 1518) General of the Reunited Inquisitions of Castile and Aragon, in which capacity he acted until his departure for Rome. During this period, Charles V left for the Netherlands in 1520, making the future pope Regent of Spain, during which time he had to deal with the Revolt of the Comuneros.
Read more about this topic: Pope Adrian VI
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