POLG2

Identifiers Symbols POLG2; HP55; MTPOLB; PEOA4; POLB; POLG-BETA; POLGB External IDs OMIM: 604983 MGI: 1354947 HomoloGene: 5221 GeneCards: POLG2 Gene EC number 2.7.7.7

Gene Ontology
Molecular function	• single-stranded DNA binding • DNA-directed DNA polymerase activity • protein binding • identical protein binding
Cellular component	• mitochondrial chromosome • mitochondrion • mitochondrial nucleoid
Biological process	• DNA replication • DNA-dependent DNA replication • DNA repair
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 11232 50776 Ensembl ENSG00000256525 ENSMUSG00000020718 UniProt Q9UHN1 Q9QZM2 RefSeq (mRNA) NM_007215 NM_015810 RefSeq (protein) NP_009146 NP_056625 Location (UCSC) Chr 17:
62.47 – 62.49 Mb Chr 11:
106.77 – 106.78 Mb PubMed search

DNA polymerase subunit gamma-2, mitochondrial is an protein that in humans is encoded by the POLG2 gene. The POLG2 gene encodes a 55 kDa accessory subunit protein that imparts high processivity and salt tolerance to the catalytic subunit of DNA polymerase gamma, encoded by the POLG gene.