Pierre-Antoine may refer to:
- Pierre-Antoine Bellange (1760-1844), French furniture designer
- Pierre-Antoine Cousteau (1906-1958), French far right polemeicist and journalist
- Pierre-Antoine Dorion (circa 1789-1850), businessman and political figure in Lower Canada
- Pierre-Antoine Lebrun (1785-1873), French poet
- Pierre-Antoine Tabeau (1782-1835), Roman Catholic priest and vicar general
- Stade Pierre-Antoine, a multi-use stadium
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