Clinical Significance
Gene knockout of phospholamban results in animals with hyperdynamic hearts, with little apparent negative consequence.
Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure .
Read more about this topic: Phospholamban
Famous quotes containing the word significance:
“History is the interpretation of the significance that the past has for us.”
—Johan Huizinga (1872–1945)