Long-term Use
A 2005 paper published in Biological Psychiatry found that "...compared to Navajos with minimal substance use, the peyote group showed no significant deficits on the Rand Mental Health Inventory (RMHI) or any neuropsychological measures...", and that they scored significantly better than non-users on the "general positive affect" and "psychological well-being" measures of the RMHI, a standard instrument used to diagnose psychological problems and determine overall mental health. By contrast, alcohol abusers did significantly worse than the control group (non-users) in all measures of the RMHI.
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