Peregrine Hoby (1 September 1602 – 6 May 1679), was an English politician who sat in the House of Commons at various times between 1640 and 1679.
Hoby was the illegitimate son and heir of Sir Edward Hoby of Bisham Abbey in Berkshire, a favourite of James I. He was High Sheriff of Berkshire in 1640. In November 1640 he was elected Member of Parliament for Great Marlow in the Long Parliament in a disputed election. He was excluded in Pride's Purge in December 1648. In 1659 he was elected MP for Great Marlow in the Third Protectorate Parliament. He was also elected in 1660 for the Convention Parliament and in 1661 for the Cavalier Parliament. He sat until 1679 and died later in the same year at the age of 76.
Hoby married Katherine Doddington (died 1687) daughter & coheiress of Sir William Doddington of Breamore House in Hampshire, and they had four sons and one daughter. His eldest son, Edward (1634–1675), was created a baronet by King Charles II in 1666; he died before his father and Peregrine's heir was his second son, John (1635–1702), who also inherited his brother's baronetcy by special remainder.