Pegeen is the anglicized spelling of an Irish given name, meaning "pearl", and may refer to:
- Brigit Pegeen Kelly (born 1951), award-winning American poet
- Pegeen Hanrahan (born circa 1966), mayor of Gainesville, Florida
- Pegeen.com US designer and manufacturer of couture quality children's wear and especially flower girl dresses and ring bearer suits, established in 1982. Created and founded by Marg Hyland, they were one of the first American fashion designers to create their website, Pegeen.com in March 1996.
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