Pd-l1

PD-L1

Identifiers Symbols CD274; B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1 External IDs OMIM: 605402 MGI: 1926446 HomoloGene: 8560 GeneCards: CD274 Gene

Gene Ontology
Molecular function	• protein binding
Cellular component	• plasma membrane • external side of plasma membrane • endomembrane system • integral to membrane • extracellular vesicular exosome
Biological process	• immune response • signal transduction • cell surface receptor signaling pathway • T cell costimulation • positive regulation of T cell proliferation • negative regulation of T cell proliferation • positive regulation of interleukin-10 secretion
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 29126 60533 Ensembl ENSG00000120217 ENSMUSG00000016496 UniProt Q9NZQ7 Q9EP73 RefSeq (mRNA) NM_001267706 NM_021893 RefSeq (protein) NP_001254635 NP_068693 Location (UCSC) Chr 9:
5.45 – 5.47 Mb Chr 19:
29.37 – 29.39 Mb PubMed search

Programmed cell death 1 ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene.