PAX2
| Gene Ontology | |
|---|---|
| Molecular function | • core promoter proximal region sequence-specific DNA binding • DNA binding • protein binding • superoxide-generating NADPH oxidase activity • transcription regulatory region DNA binding • C2H2 zinc finger domain binding |
| Cellular component | • nucleus • lysosome • microtubule organizing center • protein-DNA complex • centriolar satellite • protein complex |
| Biological process | • negative regulation of transcription from RNA polymerase II promoter • urogenital system development • branching involved in ureteric bud morphogenesis • cell fate determination • mesonephros development • neural tube closure • optic cup morphogenesis involved in camera-type eye development • mesenchymal to epithelial transition involved in metanephros morphogenesis • retinal pigment epithelium development • transcription, DNA-dependent • transcription from RNA polymerase II promoter • axonogenesis • mesodermal cell fate specification • aging • visual perception • glial cell differentiation • optic nerve development • optic nerve morphogenesis • optic nerve structural organization • vestibulocochlear nerve formation • pancreas development • response to nutrient levels • regulation of metanephros size • ureter maturation • pronephric field specification • inner ear morphogenesis • camera-type eye development • negative regulation of apoptotic process • negative regulation of programmed cell death • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • protein kinase B signaling cascade • negative regulation of transcription, DNA-dependent • positive regulation of transcription, DNA-dependent • negative regulation of cytolysis • positive regulation of transcription from RNA polymerase II promoter • pronephros development • brain morphogenesis • stem cell differentiation • positive regulation of epithelial cell proliferation • mesenchymal to epithelial transition • paramesonephric duct development • optic chiasma development • cellular response to hydrogen peroxide • cellular response to mechanical stimulus • cellular response to retinoic acid • cellular response to glucose stimulus • cellular response to epidermal growth factor stimulus • metanephric mesenchyme development • positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis • metanephric mesenchymal cell differentiation • mesonephric tubule formation • mesonephric duct development • nephric duct formation • ureter development • ureter morphogenesis • metanephric collecting duct development • metanephric epithelium development • metanephric distal convoluted tubule development • metanephric nephron tubule formation • positive regulation of metanephric glomerulus development • negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis • regulation of metanephric nephron tubule epithelial cell differentiation • reactive oxygen species metabolic process • cochlea development • cochlea morphogenesis • positive regulation of branching involved in ureteric bud morphogenesis • negative regulation of mesenchymal cell apoptotic process involved in metanephros development • negative regulation of apoptotic process involved in metanephric collecting duct development • negative regulation of apoptotic process involved in metanephric nephron tubule development • negative regulation of reactive oxygen species metabolic process • positive regulation of metanephric DCT cell differentiation • positive regulation of optic nerve formation |
| Sources: Amigo / QuickGO | |
102.5 – 102.59 Mb
44.76 – 44.84 Mb
Paired box gene 2, also known as PAX2 is a protein which in humans is encoded by the PAX2 gene.
Read more about PAX2: Function, Clinical Significance, Interactions, See Also