Orvan Hess - Early Use of Penicillin

Early Use of Penicillin

On March 14, 1942, John Bumstead and Hess became the first doctors in the world to successfully treat a patient (Anne Miller) with penicillin.

“Doctors had done everything possible, both surgically and medically,” Dr. Hess said in a 1998 interview with Katie Krauss, the editor of Yale-New Haven Magazine and one of the many babies Dr. Hess delivered. “I went to see her and knew she was dying.”
Dr. Hess went to talk to her internist, Dr. Bumstead, and found him asleep in the library. “While I was waiting for him to wake up,” Dr. Hess said, “I sat and read the latest Reader's Digest, in which there was an article called ‘Germ Killers From Earth’, about the use of soil bacteria to kill streptococcal infection in animals.”
He asked Dr. Bumstead, “Wouldn’t it be wonderful if we had something like this gramicidin mentioned in the Reader’s Digest?” This prompted Dr. Bumstead to speak with some colleagues who were studying penicillin and to obtain some for the patient, Anne Miller. The day after her first injection, Mrs. Miller’s fever broke. She lived to be 90 years old, dying in 1999.

New York Times

Hess received the American Medical Association’s Scientific Achievement Award in 1979 for his work on this case.

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