Nyctimene may mean:
- Nyctimene (genus), a genus of bats in the Pteropodidae family
- Nyctimene (mythology), a character in Ovid's Metamorphoses: the daughter of Epopeus, a king of Lesbos
- 2150 Nyctimene (1977 TA), an inner main-belt asteroid discovered on October 13, 1977 by W. Sebok at Palomar