The Company
Nuvelo, Inc. was located at San Carlos, California and had approximately 250 employees. The Company’s development pipeline included:
- Alfimeprase, a direct-acting fibrinolytic in Phase II development for the treatment of thrombotic-related disorders, including acute ischemic stroke and catheter occlusion.
- NU172, a direct thrombin inhibitor in Phase I development for use as a short-acting anticoagulant during medical or surgical procedures.
- rNAPc2, an anti-thrombin anticoagulant being developed for the treatment of thrombosis in metastatic colorectal carcinoma.
- NU206, a preclinical candidate for the treatment of chemotherapy and radiation therapy-induced mucositis and inflammatory bowel disease.
In addition, Nuvelo had research programs in leukemia therapeutic antibodies and Wnt signaling pathway therapeutics to expand its drug pipeline and create additional partnering and licensing opportunities.
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