Junction List
| County | Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|---|
| Union |
Waxhaw | 0 | 0 | NC 75 (Main Street) – Monroe, Lancaster | NC 16 begins |
| Weddington | 6.5 | 10.5 | Rea Road | ||
| 7 | 11 | NC 84 east (Weddington Road) – Monroe | |||
| Mecklenburg |
Charlotte | 10 | 16 | I-485 (Governor James G. Martin Freeway) – Pineville, Concord | |
| 13 | 21 | NC 51 (Pineville-Matthews Road) | |||
| 22 | 35 | I-277 south / US 74 west to NC 27 (John Belk Freeway) | End I-277 south and US 74 west overlaps | ||
| NC 16 overlaps with Interstate 277 (exits 2A to 5) | |||||
| 24.5 | 39.4 | I-77 / I-277 / US 21 (Bill Lee Freeway) – Statesville, Columbia | North end of I-277 overlap | ||
| 25 | 40 | Beatties Ford Road–– Johnson C. Smith University | |||
| 26.5 | 42.6 | I-85 – Greensboro, Spartanburg | |||
| 32 | 51 | I-485 (Craig Lawing Freeway) – Pineville, Huntersville | |||
| Gaston |
Lucia | 35 | 56 | To NC 273 (Lucia Riverbend Highway) | |
| 37.5 | 60.4 | NC 16 Bus. north (Lucia Riverbend Highway) |
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| Lincoln |
Lowesville | 42 | 68 | NC 73 – Lincolnton, Huntersville | |
| Catawba |
51 | 82 | NC 150 – Lincolnton, Mooresville | ||
| 53 | 85 | NC 16 Bus. south – Denver |
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| 61.5 | 99.0 | NC 16 Bus. north (Charlotte Highway) |
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| 62.5 | 100.6 | NC 10 – Catawba | |||
| Conover | 65.5 | 105.4 | US 70 (Conover Boulevard East) – Conover, Claremont | ||
| 67 | 108 | I-40 – Conover, Hickory, Statesville | |||
| 67.2 | 108.1 | NC 16 Bus. south (1st Avenue North and 1st Avenue South) |
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| Alexander |
Taylorsville | 81 | 130 | US 64 – Lenoir, Statesville | |
| 82.5 | 132.8 | NC 90 (Main Street) | Brief .5-mile (0.80 km) concurrency | ||
| Wilkes |
Moravian Falls | 96 | 154 | NC 18 south – Lenoir | South end of NC 18 overlap |
| Wilkesboro | 99.5 | 160.1 | US 421 south / NC 18 north – Winston-Salem | South end of US 421 and north end of NC 18 overlaps | |
| NC 16 overlaps with US 421 (mile markers 283–287) | |||||
| 104 | 167 | US 421 north – Boone | North end of US 421 overlap | ||
| Ashe |
120 | 193 | Blue Ridge Parkway | ||
| 120.5 | 193.9 | NC 163 west – West Jefferson | |||
| 127 | 204 | NC 88 east – Laurel Springs, Sparta | East end of NC 88 overlap | ||
| Jefferson | 130 | 209 | US 421 south / NC 88 west – Jefferson, West Jefferson | South end of US 221 and west end of NC 88 overlaps | |
| 132 | 212 | US 221 north – Twin Oaks | North end of US 221 overlap | ||
| 136 | 219 | Old Highway 16 – Crumpler | |||
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Read more about this topic: North Carolina Highway 16
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