Plot
The story of No More Heroes 2 is told with normal cutscenes following Travis' journey, interspersed with scenes of a woman at a peep show dictating the story's events to an unknown observer.
Three years have passed since Travis Touchdown became the top assassin in the United Assassins Association (UAA) and walked away (what happened to him throughout said years is never explained). Now, he returns to Santa Destroy and fights Skelter Helter, who seeks revenge on Travis for killing his older brother Helter Skelter prior to the first game. After winning the battle, he meets Sylvia Christel again, who informs him he is now ranked 51st. The nearly-dead Skelter Helter interrupts them and warns Travis that he and his co-conspirators will still have their revenge.
The same night, a group of criminals kill Travis's best friend, Bishop, and throw his head through Travis's window in a paper bag. Travis seeking revenge, asks Sylvia to set up the next fight. Sylvia tells him that the one who ordered the killing was Jasper Batt, Jr., the CEO of Pizza Bat and first-ranked assassin. In the first game, Travis stopped three different attempts by Pizza Bat (called Pizza Butt back then) to expand into Santa Destroy by assassinating the CEOs. In the three years since, with Travis out of the picture, Pizza Bat successfully opened a headquarters in Santa Destroy and bought out practically every business in town. Travis resolves to climb to the ranks to get a chance for revenge on Jasper.
Travis fights and defeats rap star Nathan Copeland. He then meets football star Charlie MacDonald and his cheerleaders, who transform into a giant Mech called the Santa Death Parade. Travis defeats them in his own mech, the Glastonbury, built by Dr. Naomi and based on a mech from his favorite anime. He feels remorse for the cheerleaders, explaining that they were harmless, but backpedals after Sylvia offers to nullify his victory. He also spares the optional challenger (the only way to fight her is by going back to the motel after beating Charlie) Kimmy Howell, commenting that he "can't kill a co-ed". He also begins to fight the supernatural, facing Matt Helms and Cloe Walsh.
Sylvia organizes a battle royale with twelve assassins, including Travis. Dr. Letz Shake kills all of the other assassins and when Travis enters the arena, Letz Shake reveals to him that he has frozen Henry in Carbonite . After Travis rescues Henry, he meets Shinobu, who now idolizes him and calls him “Master.” At Sylvia's request, she fought and defeated Million Gunman and New Destroyman for Travis. Shinobu advances on Travis, but he turns her away because he feels "like the pervy teacher in a porno". Rejected, she steps out and doesn’t return afterwards.
Travis fights a grueling battle against Ryuji. Travis crows triumphantly after Ryuji concedes, but Sylvia kills him in cold blood, criticizing Travis for showing mercy. Henry, suffering from hibernation sickness, fights Mimmy (a mixture of the anime girls and robots Travis watches) in a nightmare before awakening. He reconciles with Travis and kills the next three assassins for him. Travis fights Margaret Moonlight, a gothic Lolita, and Captain Vladimir, a cosmonaut, and convinces Sylvia not to destroy the latter's body. After defeating ascetic Alice Twilight, the penultimate assassin, he decides he is fed up with the ranked battles and the UAA. He berates Sylvia, insisting that assassins are human and that they shouldn't have to die for entertainment like its some kind of video game. He promises to tear down the UAA after defeating Jasper. Sylvia then arrives at Travis's motel room and sleeps with him, finally fulfilling her promise from the first game.
Travis fights his way through the Pizza Bat headquarters to meet Jasper in his office. Jasper reveals that he was seeking revenge for his father and two brothers, the previous Pizza Bat CEOs Travis killed in the first game. Henry enters and helps Travis defeat him. After defeating his second form, Jasper becomes a giant parade balloon, which Henry refuses to fight and destroys the roof with one swipe. This final form is destroyed after Travis leaps out the office and slices it in half. Sylvia, riding Travis's motorcycle, catches him and drops him off at his motel.
A scene after the credits reveals that the woman at the peep show is Sylvia, who took the job after the UAA's collapse, and that Travis himself has been listening to Sylvia's story about his exploits. The two have a tearful reunion as Travis informs her that they need to return to Santa Destroy for an unknown purpose.
Read more about this topic: No More Heroes 2: Desperate Struggle
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