History
Nitrous oxide as a single gas was first used as a medical analgesic in 1844 by American dentist Horace Wells, growing in popularity in the late 1800s. Negative side effects were found from the hypoxia caused by a lack of oxygen, and the requirement to have at least 21% oxygen content in the gas was discovered (the same percentage as in air).
In 1911, the anaesthetist Arthur Ernest Guedel first described the use of self-administration of a nitrous oxide and oxygen mix.
It was not until 1961 that the first paper was published by Michael Tunstall et al. describing the administration of a pre-mixed 50:50 nitrous oxide and oxygen mix, which led to the commercialisation of the product.
Read more about this topic: Nitrous Oxide And Oxygen
Famous quotes containing the word history:
“When the history of this period is written, [William Jennings] Bryan will stand out as one of the most remarkable men of his generation and one of the biggest political men of our country.”
—William Howard Taft (1857–1930)
“When we of the so-called better classes are scared as men were never scared in history at material ugliness and hardship; when we put off marriage until our house can be artistic, and quake at the thought of having a child without a bank-account and doomed to manual labor, it is time for thinking men to protest against so unmanly and irreligious a state of opinion.”
—William James (1842–1910)
“If you look at the 150 years of modern China’s history since the Opium Wars, then you can’t avoid the conclusion that the last 15 years are the best 15 years in China’s modern history.”
—J. Stapleton Roy (b. 1935)