Niobium(V) Chloride - Uses

Uses

Niobium(V) chloride is the main precursor to the alkoxides of niobium, which find niche uses in sol-gel processing. It is also the precursor to many other laboratory reagents.

In organic synthesis, NbCl5 is a specialized Lewis acid in activating alkenes for the carbonyl-ene reaction and the Diels-Alder reaction. Niobium chloride can also generate N-acyliminium compounds from certain pyrrolidines which are substrates for nucleophiles such as allyltrimethylsilane, indole, or the silyl enol ether of benzophenone.

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