Other
- HMAS Newcastle, an Adelaide class frigate of the Royal Australian Navy
- HMS Newcastle, a name given to eight ships of the British Royal Navy
- Newcastle Brown Ale, a brand of beer produced by Scottish & Newcastle
- New Castle (Stuttgart), a palace in Stuttgart, Germany
- New Castle Correctional Facility, a prison located in New Castle, Indiana
- New Castle School of Trades, a technical trades school in Pulaski, Pennsylvania
- Newcastle disease, a highly contagious bird disease
- Newcastle, an Athlon 64 processor core revision
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