Gene Ontology | |
---|---|
Molecular function | • protein binding • protein C-terminus binding • electron carrier activity • Rac GTPase binding |
Cellular component | • acrosomal vesicle • nucleolus • cytoplasm • cytosol • phagolysosome • NADPH oxidase complex |
Biological process | • antigen processing and presentation of peptide antigen via MHC class I • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • superoxide metabolic process • cellular defense response • aging • response to glucose stimulus • response to activity • response to lipopolysaccharide • response to progesterone stimulus • cellular response to hormone stimulus • response to laminar fluid shear stress • response to drug • superoxide anion generation • antigen processing and presentation of exogenous peptide antigen via MHC class I • positive regulation of neuron apoptotic process • innate immune response • respiratory burst • positive regulation of blood pressure • interaction with host • response to hyperoxia • phagosome maturation |
Sources: Amigo / QuickGO |
183.52 – 183.56 Mb
152.81 – 152.84 Mb
Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.
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