Nesoryzomys fernandinae, also known as the Fernandina Nesoryzomys, Fernandina Rice Rat, or Fernandina Galápagos Mouse, is a species of rodent in the genus Nesoryzomys of family Cricetidae. It is found only on Fernandina in the Galápagos Islands (part of Ecuador), which it shares with N. indefessus narboroughi. Its natural habitat is subtropical or tropical dry shrubland.