Negative selection may refer to:
- In biology:
- Negative selection (natural selection), in natural selection it refers to the selective removal of rare alleles that are deleterious
- Negative selection (artificial selection), in artificial selection it refers to where negative, rather than positive, traits of a species are selected for
- In politics:
- Negative selection (politics), is a process that occurs in rigid hierarchies, most notably dictatorships
- In immunology:
- Negative selection (immunology) T-cells that recognize self MHC molecules (and peptides) with high affinity are deleted from the repertoire of cells. Central tolerance is produced. Avoids auto-immunity. Occurs after positive selection.
Famous quotes containing the words negative and/or selection:
“Parents need to recognize that the negative behavior accompanying certain stages is just a small part of the total child. It should not become the main focus or be pushed into the limelight.”
—Saf Lerman (20th century)
“Historians will have to face the fact that natural selection determined the evolution of cultures in the same manner as it did that of species.”
—Konrad Lorenz (1903–1989)