Negative selection may refer to:
- In biology:
- Negative selection (natural selection), in natural selection it refers to the selective removal of rare alleles that are deleterious
- Negative selection (artificial selection), in artificial selection it refers to where negative, rather than positive, traits of a species are selected for
- In politics:
- Negative selection (politics), is a process that occurs in rigid hierarchies, most notably dictatorships
- In immunology:
- Negative selection (immunology) T-cells that recognize self MHC molecules (and peptides) with high affinity are deleted from the repertoire of cells. Central tolerance is produced. Avoids auto-immunity. Occurs after positive selection.
Famous quotes containing the words negative and/or selection:
“Coming out, all the way out, is offered more and more as the political solution to our oppression. The argument goes that, if people could see just how many of us there are, some in very important places, the negative stereotype would vanish overnight. ...It is far more realistic to suppose that, if the tenth of the population that is gay became visible tomorrow, the panic of the majority of people would inspire repressive legislation of a sort that would shock even the pessimists among us.”
—Jane Rule (b. 1931)
“The books for young people say a great deal about the selection of Friends; it is because they really have nothing to say about Friends. They mean associates and confidants merely.”
—Henry David Thoreau (1817–1862)