Negative selection may refer to:
- In biology:
- Negative selection (natural selection), in natural selection it refers to the selective removal of rare alleles that are deleterious
- Negative selection (artificial selection), in artificial selection it refers to where negative, rather than positive, traits of a species are selected for
- In politics:
- Negative selection (politics), is a process that occurs in rigid hierarchies, most notably dictatorships
- In immunology:
- Negative selection (immunology) T-cells that recognize self MHC molecules (and peptides) with high affinity are deleted from the repertoire of cells. Central tolerance is produced. Avoids auto-immunity. Occurs after positive selection.
Famous quotes containing the words negative and/or selection:
“In a country where misery and want were the foundation of the social structure, famine was periodic, death from starvation common, disease pervasive, thievery normal, and graft and corruption taken for granted, the elimination of these conditions in Communist China is so striking that negative aspects of the new rule fade in relative importance.”
—Barbara Tuchman (1912–1989)
“The books for young people say a great deal about the selection of Friends; it is because they really have nothing to say about Friends. They mean associates and confidants merely.”
—Henry David Thoreau (1817–1862)