Nanos 3' UTR translation control element is a cis-regulatory element in the 3' untranslated region (3'UTR) of the messenger RNA which encodes the Nanos protein. The Nanos protein in Drosophila is required for correct morphogenesis (anterior/posterior patterning) in the Drosophila embryo. Translation of the Nanos mRNA is repressed in the bulk cytoplasm and activated in the posterior region. The translation control element (TCE) in the 3'UTR forms a Y-shaped secondary structure, part of which is recognised by the Smaug protein and leads to translational repression.
Famous quotes containing the words translation, control and/or element:
“Translation is the paradigm, the exemplar of all writing.... It is translation that demonstrates most vividly the yearning for transformation that underlies every act involving speech, that supremely human gift.”
—Harry Mathews (b. 1930)
“Physical nature lies at our feet shackled with a hundred chains. What of the control of human nature? Do not point to the triumphs of psychiatry, social services or the war against crime. Domination of human nature can only mean the domination of every man by himself.”
—Johan Huizinga (1872–1945)
“Justice has its anger, my lord Bishop, and the wrath of justice is an element of progress. Whatever else may be said of it, the French Revolution was the greatest step forward by mankind since the coming of Christ. It was unfinished, I agree, but still it was sublime. It released the untapped springs of society; it softened hearts, appeased, tranquilized, enlightened, and set flowing through the world the tides of civilization. It was good. The French Revolution was the anointing of humanity.”
—Victor Hugo (1802–1885)