NACA (gene)

NACA (gene)

Identifiers Symbols NACA; NACA1 External IDs OMIM: 601234 MGI: 106095 HomoloGene: 123861 GeneCards: NACA Gene EC number 5.3.99.3

Gene Ontology
Molecular function	• DNA binding • transcription coactivator activity • protein binding • TBP-class protein binding
Cellular component	• nucleus • cytoplasm • nascent polypeptide-associated complex
Biological process	• cardiac ventricle development • transcription, DNA-dependent • translation • negative regulation of striated muscle cell apoptotic process • protein transport • virus-host interaction • skeletal muscle tissue regeneration • positive regulation of skeletal muscle tissue growth • regulation of skeletal muscle fiber development • heart trabecula morphogenesis • negative regulation of transcription from RNA polymerase II promoter involved in heart development • positive regulation of transcription from RNA polymerase II promoter involved in heart development • positive regulation of cell proliferation involved in heart morphogenesis
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4666 17938 Ensembl ENSG00000196531 ENSMUSG00000061315 UniProt Q13765 Q3THR6 RefSeq (mRNA) NM_001113201 NM_013608 RefSeq (protein) NP_001106673 NP_038636 Location (UCSC) Chr 12:
57.11 – 57.13 Mb Chr 10:
127.44 – 127.45 Mb PubMed search

Nascent-polypeptide-associated complex alpha polypeptide, also known as NACA, is a protein which in humans is encoded by the NACA gene.